1 West Building, 99 Yanxiang Road, Xi’an,
Shaanxi, Province, 710054,P. R. China
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Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
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Lab Director II (实验室主任II类)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
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Principal Investigator at the level of Professor,
Group Leader I (研究小组主任I类)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
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Postdoctoral Associate (Advisor: Prof. Stephen L. Buchwald)
Massachusetts Institute of Technology, Cambridge, MA, USA
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Research chemist, Basilea Pharmaceutica (China) Ltd, Haimen, China
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Research chemist, Chinese Wisdom Institute of Medicine and Wisdom Pharmaceutica Co. Ltd, Haimen, China
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Ph.D. in Organic Chemistry (Advisor: Prof. Dirk Menche)
Dissertation: Total synthesis of etnangien and studies towards the
total synthesis of rhizopodin
Heidelberg University, Heidelberg, and Helmholtz Center for Infection Research (HZI), Braunschweig, Germany
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M.S. in Organic Chemistry (Advisor: Prof. Zheng-Ming Li)
Dissertation: Synthesis and biological activities of novel
Nankai University, Tianjin, China
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B.S. in Chemistry, Shanxi Normal University, Linfen, China
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Thieme Chemistry Journal Award, Germany
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“陕西省青年科技新星”, Shaanxi Province
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The highest honor (summa cum laude) for the Ph.D. dissertation in
Heidelberg University, Germany
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Homogeneous Catalysis • Medicinal Chemistry • Natural Products• Flow Chemistry
1. Development of novel catalytic reactions for efficient construction of functionalized
complex molecules that may be used as chemical probes in chemical biology or as organic
2. Total synthesis of bioactive natural products and their analogs for drug discovery and
3. Continuous microflow synthesis for more user-friendly and more sustainable, efficient
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Representative Publications
1.Guanghui Wang, Liang Xu andPengfei Li,* Double N,B-type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation,J. Am. Chem. Soc.2015, DOI: 10.1021/jacs.5b05252.
2. Guanghu Tong, Zhi Liu,Pengfei Li,* Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative Dearomatization Approach,Org. Lett.2014, 16,2288-2291.
3. Dongmei Lu,* Chao Wu,Pengfei Li,* 3-Center-5-Electron Boryl Radicals with σ0π1Ground State Electronic Structure,Org. Lett.2014, 16,1486-1489.
4. Liang Xu,Siyi Ding,Pengfei Li,* Site-differentiated Polyboron Arenes Prepared by Direct C-H Borylation and Their Highly Selective Suzuki-Miyaura Cross-Coupling Reactions,Angew. Chem. Int. Ed.2014, 53, 1822-1826.
Highlighted bySYNPACTS: Synlett,2014, 1799-1802.
Highlighted byChinese J. Org. Chem.2014,34, 836.
AndXi’an Jiaotong University web news.
5. Xiaowu Liu, Fei Xiong, Xuanping Huang, Liang Xu,Pengfei Li,* and Xiaoxing Wu,* Copper-Catalyzed Trifluoromethylation-Triggered Neophyl-Type Rearrangement of α,α-Diaryl Allylic Alcohols,Angew. Chem. Int. Ed.2013, 52,6962-6966.
Highlighted bySYNPACTS: Synlett,2013,24, 1882-1886.
Highlighted byChinese J. Org. Chem.2013,33, 1850.
6.Pengfei Li,* Jason S. Moore, Klavs F. Jensen,* A Microfluidic System for the Continuous Recycling of Unmodified Homogeneous Palladium Catalysts via Liquid-Liquid Phase Separation,ChemCatChem2013,5, 1729-1733.
7.Pengfei Li, Stephen L. Buchwald,* Continuous-Flow Synthesis of 3,3-Disubstituted Oxindoles by a Palladium-Catalyzed -Arylation/Alkylation Sequence,Angew. Chem. Int. Ed.2011, 50,6396-6400.
8.Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Stereoselective Total Synthesis of Etnangien and Etnangien Methyl Ester,J. Org. Chem.2010,75, 2429-2444.
9.Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Total Synthesi of Etnangien,J. Am. Chem. Soc.2009,131,11678-11679.
10.Pengfei Li, Dirk Menche*, Cycloadditions in the Total Synthesis of Sporolide B,Angew. Chem. Int.Ed.2009,48, 5078-5080.
For a full list of publications, see Research ID: E-3211-2012.
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