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李鹏飞(兼聘)
来源: | 作者: | 发布时间:2014-06-19 | 浏览:1136次

Dr. Pengfei Li's Blog:

 

Address:

1 West Building, 99 Yanxiang Road, Xi’an,

Shaanxi, Province, 710054,P. R. China

Tel: 86-29-83395337

Fax: 86-29-83395132

 

 

Employment

Jul/2015 –

Professor (教授)

Organic Chemistry Research Center (OCRC)

Frontier Institute of Science and Technology (FIST),

Xi’an Jiaotong University (XJTU), Xi’an, China

May/2014 –Jun/2015

Lab Director II (实验室主任II类)

Organic Chemistry Research Center (OCRC)

Frontier Institute of Science and Technology (FIST),

Xi’an Jiaotong University (XJTU), Xi’an, China

Nov/2011 – Apr/2014

Principal Investigator at the level of Professor,

Group Leader I (研究小组主任I类)

Organic Chemistry Research Center (OCRC)

Frontier Institute of Science and Technology (FIST),

Xi’an Jiaotong University (XJTU), Xi’an, China

Mar/2010 – Oct/2011

Postdoctoral Associate (Advisor: Prof. Stephen L. Buchwald)

Department of Chemistry

Massachusetts Institute of Technology, Cambridge, MA, USA

Apr/2005 – Sep/2006

Research chemist, Basilea Pharmaceutica (China) Ltd, Haimen, China

Jul/2004 – Mar/2005

Research chemist, Chinese Wisdom Institute of Medicine and Wisdom Pharmaceutica Co. Ltd, Haimen, China

 

Education

 

Oct/2006 – Feb/2010

Ph.D. in Organic Chemistry (Advisor: Prof. Dirk Menche)

Dissertation: Total synthesis of etnangien and studies towards the

total synthesis of rhizopodin

Heidelberg University, Heidelberg, and Helmholtz Center for Infection Research (HZI), Braunschweig, Germany

Sep/2001 – Jun/2004

M.S. in Organic Chemistry (Advisor: Prof. Zheng-Ming Li)

Dissertation: Synthesis and biological activities of novel

sulfonylurea compounds

Nankai University, Tianjin, China

Sep/1997 – Jul/2001

B.S. in Chemistry, Shanxi Normal University, Linfen, China

Honors and Awards

 

2015

Thieme Chemistry Journal Award, Germany

2015

“陕西省青年科技新星”, Shaanxi Province

2010

The highest honor (summa cum laude) for the Ph.D. dissertation in

Heidelberg University, Germany

 

Research Interests

 

Homogeneous Catalysis • Medicinal Chemistry • Natural Products• Flow Chemistry

1. Development of novel catalytic reactions for efficient construction of functionalized

complex molecules that may be used as chemical probes in chemical biology or as organic

materials

2. Total synthesis of bioactive natural products and their analogs for drug discovery and

development

3. Continuous microflow synthesis for more user-friendly and more sustainable, efficient

processes




Representative Publications

 

1.Guanghui Wang, Liang Xu andPengfei Li,* Double N,B-type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation,J. Am. Chem. Soc.2015, DOI: 10.1021/jacs.5b05252.

2. Guanghu Tong, Zhi Liu,Pengfei Li,* Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative Dearomatization Approach,Org. Lett.2014, 16,2288-2291.

3. Dongmei Lu,* Chao Wu,Pengfei Li,* 3-Center-5-Electron Boryl Radicals with σ0π1Ground State Electronic Structure,Org. Lett.2014, 16,1486-1489.

4. Liang Xu,Siyi Ding,Pengfei Li,* Site-differentiated Polyboron Arenes Prepared by Direct C-H Borylation and Their Highly Selective Suzuki-Miyaura Cross-Coupling Reactions,Angew. Chem. Int. Ed.2014, 53, 1822-1826.

Highlighted bySYNPACTS: Synlett,2014, 1799-1802.

Highlighted byChinese J. Org. Chem.2014,34, 836.

AndXi’an Jiaotong University web news.

5. Xiaowu Liu, Fei Xiong, Xuanping Huang, Liang Xu,Pengfei Li,* and Xiaoxing Wu,* Copper-Catalyzed Trifluoromethylation-Triggered Neophyl-Type Rearrangement of α,α-Diaryl Allylic Alcohols,Angew. Chem. Int. Ed.2013, 52,6962-6966.

Highlighted bySYNPACTS: Synlett,2013,24, 1882-1886.

Highlighted byChinese J. Org. Chem.2013,33, 1850.

6.Pengfei Li,* Jason S. Moore, Klavs F. Jensen,* A Microfluidic System for the Continuous Recycling of Unmodified Homogeneous Palladium Catalysts via Liquid-Liquid Phase Separation,ChemCatChem2013,5, 1729-1733.

7.Pengfei Li, Stephen L. Buchwald,* Continuous-Flow Synthesis of 3,3-Disubstituted Oxindoles by a Palladium-Catalyzed -Arylation/Alkylation Sequence,Angew. Chem. Int. Ed.2011, 50,6396-6400.

8.Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Stereoselective Total Synthesis of Etnangien and Etnangien Methyl Ester,J. Org. Chem.2010,75, 2429-2444.

9.Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Total Synthesi of Etnangien,J. Am. Chem. Soc.2009,131,11678-11679.

10.Pengfei Li, Dirk Menche*, Cycloadditions in the Total Synthesis of Sporolide B,Angew. Chem. Int.Ed.2009,48, 5078-5080.

For a full list of publications, see Research ID: E-3211-2012.

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