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李鹏飞 教授
作者:admin | 发布时间:2012-11-06 | 浏览:62982次

Dr. Pengfei Li (李鹏飞)
Dr. Pengfei Li's Blog:
 
Address:
1 West Building, 99 Yanxiang Road, Xi’an,
Shaanxi, Province, 710054, P. R. China
 
Tel: 86-29-83395337
Fax: 86-29-83395132
 
Employment
Jul/2015 –
Professor (教授)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
 
May/2014 –Jun/2015 
Lab Director II (实验室主任II类)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
 
Nov/2011 – Apr/2014
Principal Investigator at the level of Professor,
Group Leader I (研究小组主任I类)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
 
Mar/2010 – Oct/2011
Postdoctoral Associate (Advisor: Prof. Stephen L. Buchwald)
Department of Chemistry
Massachusetts Institute of Technology, Cambridge, MA, USA
 
Apr/2005 – Sep/2006
Research chemist, Basilea Pharmaceutica (China) Ltd, Haimen, China
 
Jul/2004 – Mar/2005
Research chemist, Chinese Wisdom Institute of Medicine and Wisdom Pharmaceutica Co. Ltd, Haimen, China
 
Education
 
Oct/2006 – Feb/2010
Ph.D. in Organic Chemistry (Advisor: Prof. Dirk Menche)
Dissertation: Total synthesis of etnangien and studies towards the
total synthesis of rhizopodin
Heidelberg University, Heidelberg, and Helmholtz Center for Infection Research (HZI), Braunschweig, Germany
Sep/2001 – Jun/2004
M.S. in Organic Chemistry (Advisor: Prof. Zheng-Ming Li)
Dissertation: Synthesis and biological activities of novel
sulfonylurea compounds
Nankai University, Tianjin, China
Sep/1997 – Jul/2001
B.S. in Chemistry, Shanxi Normal University, Linfen, China
 
Honors and Awards
 
2015
Thieme Chemistry Journal Award, Germany
2015
“陕西省青年科技新星”, Shaanxi Province
2010
The highest honor (summa cum laude) for the Ph.D. dissertation in
Heidelberg University, Germany
 
Research Interests
 
Homogeneous Catalysis • Medicinal Chemistry • Natural Products• Flow Chemistry
1.   Development of novel catalytic reactions for efficient construction of functionalized
complex molecules that may be used as chemical probes in chemical biology or as organic
materials
2.   Total synthesis of bioactive natural products and their analogs for drug discovery and
development
3.   Continuous microflow synthesis for more user-friendly and more sustainable, efficient
processes
 

Representative Publications

1.     Guanghui Wang, Liang Xu and Pengfei Li,* Double N,B-type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation, J. Am. Chem. Soc. 2015, 137, 8058-8061.


2.     Liang Xu, Shuai Zhang, Pengfei Li,* Boron-selective reactions as powerful tools for modular synthesis of diverse complex molecules, Chem. Soc. Rev. 2015, 44, DOI:10.1039/c5cs00338.

3.     Liang Xu, Siyi Ding, Pengfei Li,* Site-differentiated Polyboron Arenes Prepared by Direct C-H Borylation and Their Highly Selective Suzuki-Miyaura Cross-Coupling Reactions, Angew. Chem. Int. Ed.  2014, 53, 1822-1826.

4.     Guanghu Tong, Zhi Liu, Pengfei Li,* Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative Dearomatization Approach, Org. Lett2014, 16, 2288-2291.

5.     Xiaowu Liu, Fei Xiong, Xuanping Huang, Liang Xu, Pengfei Li,* and Xiaoxing Wu,* Copper-Catalyzed Trifluoromethylation-Triggered Neophyl-Type Rearrangement of α,α-Diaryl Allylic Alcohols, Angew. Chem. Int. Ed. 2013, 52, 6962-6966.

6.     Pengfei Li,* Jason S. Moore, Klavs F. Jensen,* A Microfluidic System for the Continuous Recycling of Unmodified Homogeneous Palladium Catalysts via Liquid-Liquid Phase Separation, ChemCatChem 20135, 1729-1733.

7.     Pengfei Li, Stephen L. Buchwald,* Continuous-Flow Synthesis of 3,3-Disubstituted Oxindoles by a Palladium-Catalyzed -Arylation/Alkylation Sequence, Angew. Chem. Int. Ed. 2011, 50, 6396-6400.

8.     Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Stereoselective Total Synthesis of Etnangien and Etnangien Methyl Ester, J. Org. Chem. 201075, 2429-2444.

9.     Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Total Synthesi of Etnangien, J. Am. Chem. Soc. 2009, 131, 11678-11679.

10.   Pengfei Li, Dirk Menche*, Cycloadditions in the Total Synthesis of Sporolide B, Angew. Chem. Int. Ed. 200948, 5078-5080.


For a full list of publications, see Research ID: E-3211-2012.
 
 
招收硕士生、博士生和博士后。
 
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